FREE / THE MOLECULE EXPLORER
Rotate computed molecular models, inspect their chemistry and trace a selected Arabidopsis signaling route. Different stereoisomers have different roles; a rendered model is not a clinical result.
Molecular learning studio
Turn the structure, inspect its chemistry and follow the plant pathway with evidence attached.
Drag to rotate. Use the zoom buttons or pinch with two fingers. Keyboard: arrows rotate, + and − zoom, 0 resets.
One computed PubChem conformer of the specified stereoisomer. The model is not an experimental crystal structure or a guaranteed receptor-bound pose. Colors and sizes are display choices.
A twelve-carbon plant signaling molecule.
Jasmonic acid belongs to the jasmonate family of plant oxylipins. Plant enzymes can modify this acid into compounds with different signaling roles.
Selected model: (1R,2R), (Z), neutral JA.
Select a highlighted feature or tap an atom to inspect the real PubChem model. Oxygen is red; nitrogen is blue; carbon is charcoal; hydrogen is pale.
Every sphere maps to a source atom. Double bonds use two sticks. Hydrogens are included in the downloadable structure.
This model is the neutral (1R,2R), (Z)-side-chain stereoisomer in PubChem CID 5281166. Natural synthesis initially produces (+)-7-iso-JA, with a different ring configuration. These forms must not be treated as one interchangeable structure.
These 3D depictions use one computed PubChem conformer of each explicitly named stereoisomer. A molecule has conformational flexibility, and the displayed neutral structure is not a measurement of its form inside a cell. These are not experimental crystallographic models or proven receptor-bound poses.
PubChem CID: 5281166. Conformer: 0050958E00000001. Complete record: 33 atoms including 18 hydrogens, 33 bonds.
Follow a simplified Arabidopsis jasmonate pathway. Select each step to see the mechanism and its primary evidence.
Peroxisomal route
In the classical route, OPR3 reduces OPDA and beta-oxidation shortens the side chain to form JA. An OPR3-independent route also exists, so OPR3 should not be called the only possible entry to JA synthesis.
This chart summarizes selected routes established in Arabidopsis thaliana. It is not every jasmonate pathway in every species. Compartment transport, other metabolites, catabolism, interacting hormones and many regulators are omitted.
JA on this pathway means a biological jasmonic-acid pool, including stereoisomers. The JA 3D tab selects the trans (1R,2R) record; the JA-Ile 3D tab selects the (+)-7-iso bioactive ligand. The arrows are a biological overview, not a claim that the displayed trans JA conformer converts directly into the displayed cis JA-Ile conformer without a stereochemical change.
For molecular and literature education. No chemical synthesis, handling, application or dose instructions are provided.
Learn, then challenge yourself
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Question 1 of 8
Jasmonate cancer research discussed here is preclinical. Findings in cultured cells, isolated components or animals do not establish prevention, cancer reduction, treatment efficacy or safety in people. Do not use these materials to self-treat or replace medical care.
